BDBM679893 5-{6-[2-(4-Chloro-2-methyl-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-3-ethoxy-thiophene- 2-carboxylic acid::US12011444, Example 108

SMILES CCOc1cc(sc1C(O)=O)-c1cc(NCCn2c(C)cc3c(Cl)cccc23)ncn1

InChI Key InChIKey=RMEBCQKRWPHROE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679893   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM679893(US12011444, Example 108 | 5-{6-[2-(4-Chloro-2-meth...)
Affinity DataIC50: 1nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM679893(US12011444, Example 108 | 5-{6-[2-(4-Chloro-2-meth...)
Affinity DataIC50: 15nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent