BDBM679782 US12011433, Compound MPA462

SMILES COc1ccc(cc1)-c1noc(CC(=O)Nc2ccc(cc2)-c2ccc(NC(=O)Cc3onc(c3-c3ccc(OC)cc3)-c3ccc(CO)cc3)cc2)c1-c1ccc(CO)cc1

InChI Key InChIKey=ZVKUMGXPHGDMSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679782   

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679782(US12011433, Compound MPA462)
Affinity DataIC50: 80nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679782(US12011433, Compound MPA462)
Affinity DataIC50: 5.00E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent