BDBM679471 1-((1R,3s,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(9-methyl-5,6,8,9,10,11-hexahydro-7H-5,9:7,11-dimethanobenzo[9]annulen-7-yl)urea::US20240182406, Example C2

SMILES CC12CC3CC(CC(C1)c1ccccc31)(C2)NC(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679471   

TargetEpoxide hydrolase 1(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM679471(1-((1R,3s,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-...)
Affinity DataIC50: 4.70nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
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Date in BDB:
9/18/2024
Entry Details
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