BDBM679131 (rac)-6-chloro-1-methyl-4-[4-(5-methyl-1,3-benzoxazol-2-yl)piperidin-1-yl]-2-oxo-7-[(oxolan-3-yl)methoxy]-1,2-dihydroquinoline-3-carboxamide::US11998539, Example 573::US11998539, Example 574::US11998539, Example 575

SMILES Cc1ccc2oc(nc2c1)C1CCN(CC1)c1c(C(N)=O)c(=O)n(C)c2cc(OCC3CCOC3)c(Cl)cc12

InChI Key InChIKey=LGHREVVLHSOREV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 679131   

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679131(US11998539, Example 573 | (rac)-6-chloro-1-methyl-...)
Affinity DataIC50: 1.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679131(US11998539, Example 573 | (rac)-6-chloro-1-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679131(US11998539, Example 573 | (rac)-6-chloro-1-methyl-...)
Affinity DataIC50: 5.60nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent