BDBM679096 (rac)-6-cyano-1-methyl-4-[4-(5-methyl-1,3-benzoxazol-2-yl)piperidin-1-yl]-2-oxo-7-[(oxolan-3-yl)oxy]-1,2-dihydroquinoline-3-carboxamide::US11998539, Example 538::US11998539, Example 539::US11998539, Example 540

SMILES Cc1ccc2oc(nc2c1)C1CCN(CC1)c1c(C(N)=O)c(=O)n(C)c2cc(OC3CCOC3)c(cc12)C#N

InChI Key InChIKey=QWXMHWVFJQOVMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 679096   

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 2.80nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent