BDBM679092 (rac)-6-cyano-1-methyl-4-{4-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-2-oxo-7-[(oxolan-3-yl)oxy]-1,2-dihydroquinoline-3-carboxamide::US11998539, Example 534::US11998539, Example 535::US11998539, Example 536

SMILES Cc1ccccc1-c1noc(n1)C1CCN(CC1)c1c(C(N)=O)c(=O)n(C)c2cc(OC3CCOC3)c(cc12)C#N

InChI Key InChIKey=BAHDOIQVSOFPFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 679092   

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679092(US11998539, Example 534 | US11998539, Example 536 ...)
Affinity DataIC50: 2nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679092(US11998539, Example 534 | US11998539, Example 536 ...)
Affinity DataIC50: 0.800nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679092(US11998539, Example 534 | US11998539, Example 536 ...)
Affinity DataIC50: 6.70nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent