BDBM678978 6-bromo-4-[4-fluoro-4-(5-methyl-1,3-benzoxazol-2-yl)piperidin-1-yl]-7-methoxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile::US11998539, Example 420

SMILES COc1cc2n(C)c(=O)c(C#N)c(N3CCC(F)(CC3)c3nc4cc(C)ccc4o3)c2cc1Br

InChI Key InChIKey=FJWRMGLUUAUFII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678978   

TargetDiacylglycerol kinase alpha(Human)
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US Patent
LigandPNGBDBM678978(US11998539, Example 420 | 6-bromo-4-[4-fluoro-4-(5...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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