BDBM678465 6-((4-chloro-1H-pyrazol-1-yl)methyl)-2-(3-methyl-1H-pyrazol-4-yl)-4-(2-methyl-2,8-diazaspiro[4.5]decan-8-yl)pyrido[3,4-d]pyrimidine ::US20240174696, Compound 190

SMILES CN1CCC2(C1)CCN(CC2)c1nc(nc2cnc(Cn3cc(Cl)cn3)cc12)-c1c[nH]nc1C

InChI Key InChIKey=GJBAVSCFKIVOKU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678465   

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandPNGBDBM678465(US20240174696, Compound 190 | 6-((4-chloro-1H-pyra...)
Affinity DataKi:  0.0260nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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