BDBM678424 3-(8-(2-(3-methyl-1H-pyrazol-4-yl)pyrido[3,4-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decan-2-yl)propan-1-ol ::US20240174696, Compound 149

SMILES Cc1n[nH]cc1-c1nc(N2CCC3(CCN(CCCO)C3)CC2)c2ccncc2n1

InChI Key InChIKey=ZHTWUTXJNNMDEE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678424   

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandPNGBDBM678424(US20240174696, Compound 149 | 3-(8-(2-(3-methyl-1H...)
Affinity DataKi:  0.0450nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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