BDBM678403 US20240174696, Compound 128

SMILES O[C@@H]1CCC[C@H]1N1CCC2(C1)CCN(CC2)c1nc(nc2cnccc12)-c1ccncc1

InChI Key InChIKey=SAQSMANEGRAMNT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 678403   

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM678403(US20240174696, Compound 128)
Affinity DataKi:  0.00600nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandPNGBDBM678403(US20240174696, Compound 128)
Affinity DataKi:  0.0730nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent