BDBM678084 N-[1- (cyclobutylmethyl)- 1H-pyrazol-4-yl]- 6-(6,7-dihydro- 4H-pyrazolo[5,1- c][1,4]oxazin-3- yl)pyridine-2- carboxamide::US20240174679, Example 9-10

SMILES O=C(Nc1cnn(CC2CCC2)c1)c1cccc(n1)-c1cnn2CCOCc12

InChI Key InChIKey=ILGRBKJSKPNILZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678084   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM678084(US20240174679, Example 9-10 | N-[1- (cyclobutylmet...)
Affinity DataIC50: 17.4nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
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