BDBM678074 N-[1-(2,6- dimethylpyridin- 4-yl)-1H- pyrazol-4-yl]-2- (1H-pyrazol-4- yl)-1,3-thiazole- 4-carboxamide::US20240174679, Example 8-4

SMILES Cc1cc(cc(C)n1)-n1cc(NC(=O)c2csc(n2)-c2cn[nH]c2)cn1

InChI Key InChIKey=SUIYQSJRSHPMCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678074   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM678074(US20240174679, Example 8-4 | N-[1-(2,6- dimethylpy...)
Affinity DataIC50: 15.1nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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