BDBM678073 N-{1-[2-(1- methylethyl) pyridin-4-yl]-1H- pyrazol-4-yl}-2- (1H-pyrazol-4- yl)-1,3-thiazole- 4-carboxamide::US20240174679, Example 8-3

SMILES CC(C)c1cc(ccn1)-n1cc(NC(=O)c2csc(n2)-c2cn[nH]c2)cn1

InChI Key InChIKey=OKRLWADYSQIWSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678073   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM678073(US20240174679, Example 8-3 | N-{1-[2-(1- methyleth...)
Affinity DataIC50: 12.9nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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