BDBM677996 N-[1-({1- [(methylsulfonyl) methyl]cyclobutyl} methyl)-1H- pyrazol-4-yl]-2- (1H-pyrazol-4- yl)-1,3-thiazole- 4-carboxamide::US20240174679, Example 1-44

SMILES CS(=O)(=O)CC1(Cn2cc(NC(=O)c3csc(n3)-c3cn[nH]c3)cn2)CCC1

InChI Key InChIKey=UVCXPNSLOFQIBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677996   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM677996(US20240174679, Example 1-44 | N-[1-({1- [(methylsu...)
Affinity DataIC50: 12.3nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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