BDBM677979 N-[1-({1- [(methylsulfanyl) methyl]cyclobu- tyl}methyl)-1H- pyrazol-4-yl]-2- (1H-pyrazol-4- yl)-1,3-thiazole- 4-carboxamide::US20240174679, Example 1-27

SMILES CSCC1(Cn2cc(NC(=O)c3csc(n3)-c3cn[nH]c3)cn2)CCC1

InChI Key InChIKey=UOTCDKDTOHTFTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677979   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM677979(US20240174679, Example 1-27 | N-[1-({1- [(methylsu...)
Affinity DataIC50: 17nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
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