BDBM677952 US20240174674, Compound 296

SMILES O[C@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1F)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12

InChI Key InChIKey=XUFWZDWCNLTRIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677952   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM677952(US20240174674, Compound 296)
Affinity DataIC50: 2.10nMAssay Description:a) 10 nL of compound dilution was transferred to each well of the test plate;b) the compound plate was centrifuged at 1000 g for 1 min;c) the test pl...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
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