BDBM677935 US20240174674, Compound 275

SMILES CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1

InChI Key InChIKey=GOIBNFSVXLLJFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677935   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM677935(US20240174674, Compound 275)
Affinity DataIC50: 0.800nMAssay Description:a) 10 nL of compound dilution was transferred to each well of the test plate;b) the compound plate was centrifuged at 1000 g for 1 min;c) the test pl...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
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