BDBM677859 US20240174674, Compound 17

SMILES CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2F)c2c3cn[nH]c3nn2c1

InChI Key InChIKey=YQRVUIYMRVZQQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677859   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM677859(US20240174674, Compound 17)
Affinity DataIC50: 2.10nMAssay Description:a) 10 nL of compound dilution was transferred to each well of the test plate;b) the compound plate was centrifuged at 1000 g for 1 min;c) the test pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent