BDBM677338 US20240174662, Example 131::US20240174662, Example 2::US20240174662, Example 290

SMILES CN1CC[C@@H]1COc1cnn(C)c1-c1ccn2nc(Nc3cc(C)nc(C)n3)cc2c1

InChI Key InChIKey=IBYBLFQNHCSFRL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 677338   

TargetSerine/threonine-protein kinase SIK2(Human)
Janssen Biotech

US Patent
LigandPNGBDBM677338(US20240174662, Example 2 | US20240174662, Example ...)
Affinity DataIC50: 0.847nMAssay Description:All steps were performed at room temperature. Compounds were pre-plated onto an assay plate using an Echo acoustic dispenser (Labcyte, E550 or E555) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Janssen Biotech

US Patent
LigandPNGBDBM677338(US20240174662, Example 2 | US20240174662, Example ...)
Affinity DataIC50: 0.847nMAssay Description:All steps were performed at room temperature. Compounds were pre-plated onto an assay plate using an Echo acoustic dispenser (Labcyte, E550 or E555) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Janssen Biotech

US Patent
LigandPNGBDBM677338(US20240174662, Example 2 | US20240174662, Example ...)
Affinity DataIC50: 0.847nMAssay Description:All steps were performed at room temperature. Compounds were pre-plated onto an assay plate using an Echo acoustic dispenser (Labcyte, E550 or E555) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent