BDBM677328 US20240174652, Example 3

SMILES CCn1c(nc2cc(ccc12)C(F)(F)F)[C@@H](NC(=O)c1cnc(C)cn1)[C@H]1COCCO1

InChI Key InChIKey=QACIHVCFPXTUBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 677328   

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677328(US20240174652, Example 3)
Affinity DataIC50: 5nMAssay Description:The in vitro activity of the compounds according to the invention may be investigated as follows:[0111]The HEK293 cell overexpressing the human metab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
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TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677328(US20240174652, Example 3)
Affinity DataIC50: 5nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent