BDBM677319 N-(2-(N-(7-bromo-quinoline-5-yl) aminosulfonyl)-pyridin-4-yl)-2-oxo-2H- chromene-8-amide::US20240174650, Compound 18

SMILES Brc1cnc2cccc(NS(=O)(=O)c3cc(NC(=O)c4cccc5ccc(=O)oc45)ccn3)c2c1

InChI Key InChIKey=HSJKXNVOYCPZAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677319   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Longivitron (Suzhou) Biotechnology Co.

US Patent
LigandPNGBDBM677319(US20240174650, Compound 18 | N-(2-(N-(7-bromo-quin...)
Affinity DataIC50: 963nMAssay Description:The SIRT2 enzyme activity assay is established based on the published studies. Firstly, peptide segment Ac-Gln-Pro-Lys-[Lys-(Ac)]-AMC, the substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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