BDBM677318 N-(2-(N-(quinoline-5-yl)aminosulfonyl)- pyridin-4-yl)-2-oxo-2H-chromene-8- amide::US20240174650, Compound 17

SMILES O=C(Nc1ccnc(c1)S(=O)(=O)Nc1cccc2ncccc12)c1cccc2ccc(=O)oc12

InChI Key InChIKey=MPKQRIXMINTJMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677318   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Longivitron (Suzhou) Biotechnology Co.

US Patent
LigandPNGBDBM677318(US20240174650, Compound 17 | N-(2-(N-(quinoline-5-...)
Affinity DataIC50: 871nMAssay Description:The SIRT2 enzyme activity assay is established based on the published studies. Firstly, peptide segment Ac-Gln-Pro-Lys-[Lys-(Ac)]-AMC, the substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent