BDBM677311 N-(2-(N-(4-phenylphenyl)amino- sulfonyl)-pyridin-4-yl)-2-oxo-2H- chromene-8-amide::US20240174650, Compound 10

SMILES O=C(Nc1ccnc(c1)S(=O)(=O)Nc1ccc(cc1)-c1ccccc1)c1cccc2ccc(=O)oc12

InChI Key InChIKey=HMGQELBFUPHXNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677311   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Longivitron (Suzhou) Biotechnology Co.

US Patent
LigandPNGBDBM677311(US20240174650, Compound 10 | N-(2-(N-(4-phenylphen...)
Affinity DataIC50: 652nMAssay Description:The SIRT2 enzyme activity assay is established based on the published studies. Firstly, peptide segment Ac-Gln-Pro-Lys-[Lys-(Ac)]-AMC, the substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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