BDBM677276 N4-cyclopropyl-N2-(1-(oxetan-3-ylmethyl)-1H-indazol-4-yl)-5-(trifluoromethyl) pyrimidine-2,4-diamine::US20240174647, Example 197

SMILES FC(F)(F)c1cnc(Nc2cccc3n(CC4COC4)ncc23)nc1NC1CC1

InChI Key InChIKey=MMVWERYXDPKNIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677276   

LigandPNGBDBM677276(US20240174647, Example 197 | N4-cyclopropyl-N2-(1-...)
Affinity DataIC50: 25nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
US Patent