BDBM677229 N4-cyclobutyl-N2-(1-methylsulfonylindazol-4-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 150

SMILES CS(=O)(=O)n1ncc2c(Nc3ncc(c(NC4CCC4)n3)C(F)(F)F)cccc12

InChI Key InChIKey=MUBAVVIFTCYJQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677229   

LigandPNGBDBM677229(US20240174647, Example 150 | N4-cyclobutyl-N2-(1-m...)
Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent