BDBM677228 (S)-N2-(1-(Methylsulfonyl)-1H-indazol-4-yl)-N4-(tetrahydrofuran-3-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 149

SMILES CS(=O)(=O)n1ncc2c(Nc3ncc(c(N[C@H]4CCOC4)n3)C(F)(F)F)cccc12

InChI Key InChIKey=JARZBDNUPRXPHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677228   

LigandPNGBDBM677228(US20240174647, Example 149 | (S)-N2-(1-(Methylsulf...)
Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
US Patent