BDBM677224 N2-(1-cyclopropylsulfonylindazol- 4-yl)-N4-(2-methoxyethyl)-5- (trifluoromethyl) pyrimidine-2,4- diamine::US20240174647, Example 145

SMILES COCCNc1nc(Nc2cccc3n(ncc23)S(=O)(=O)C2CC2)ncc1C(F)(F)F

InChI Key InChIKey=JPBOOTDJHKPLGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677224   

LigandPNGBDBM677224(US20240174647, Example 145 | N2-(1-cyclopropylsulf...)
Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent