BDBM677190 Synthesis of 2-(7-chloro-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-indazol-1-yl)acetonitrile::US20240174647, Example 111

SMILES CNc1nc(Nc2ccc(Cl)c3n(CC#N)ncc23)ncc1C(F)(F)F

InChI Key InChIKey=NUSHQOFLXBBPDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677190   

LigandPNGBDBM677190(US20240174647, Example 111 | Synthesis of 2-(7-chl...)
Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
US Patent