BDBM677154 Synthesis of N2-(1H-indazol-7-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 75

SMILES CNc1nc(Nc2cccc3cn[nH]c23)ncc1C(F)(F)F

InChI Key InChIKey=GNJHEXWCPOHLCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677154   

LigandPNGBDBM677154(US20240174647, Example 75 | Synthesis of N2-(1H-in...)
Affinity DataIC50: 25nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
US Patent