BDBM677094 N2-(1-cyclopropylsulfonylindazol-4-yl)-N4-(2-methoxyethyl)-5-(trifluoromethyl) pyrimidine-2,4-diamine::US20240174647, Example 15

SMILES CNc1nc(Nc2ccc3cnn(C)c3c2C)ncc1C(F)(F)F

InChI Key InChIKey=WJSRTPMZOVELGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677094   

LigandPNGBDBM677094(US20240174647, Example 15 | N2-(1-cyclopropylsulfo...)
Affinity DataIC50: 25nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent