BDBM677079 US20240174621, Example AR-31::WO2012118492, Example 31

SMILES Cn1cnc2ccc(Oc3c(Cl)ccc(NS(=O)(=O)N4CCCC4)c3C#N)cc2c1=O

InChI Key InChIKey=XCCAOVJRURGDKW-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 677079   

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  45.9nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  119nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  190nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  1.21E+3nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  1.20E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent