BDBM677078 US20240174621, Example AR-30::WO2012118492, Example 30

SMILES CN(C)S(=O)(=O)Nc1ccc(Cl)c(Oc2ccc3ncn(C)c(=O)c3c2)c1C#N

InChI Key InChIKey=WAKWOUWBYOMDKB-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 677078   

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  174nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  504nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  822nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  8.01E+3nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
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TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  1.04E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent