BDBM677077 US20240174633, Example 2.4

SMILES COc1cn([C@@H](C)C(=O)Nc2ccc(C(N)=O)c(F)c2)c(=O)cc1-c1c(F)c(Cl)ccc1-n1cc(nn1)C(F)(F)F

InChI Key InChIKey=JWDUTOYRMYEYFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 677077   

TargetCoagulation factor XI(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM677077(US20240174633, Example 2.4)
Affinity DataIC50: 1.20nMAssay Description:Test substances are dissolved in dimethyl sulfoxide and serially diluted in dimethyl sulfoxide (3000 μM to 0.0078 μM; resulting final conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM677077(US20240174633, Example 2.4)
Affinity DataIC50: 3.40nMAssay Description:Test substances are dissolved in dimethyl sulfoxide and serially diluted in dimethyl sulfoxide (3000 μM to 0.0078 μM; resulting final conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent