BDBM676769 (R)-5-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-::US20240166651, Example 10

SMILES CN([C@@H]1CCN(C1)c1cnc(nc1)C#N)c1ncnc2[nH]ccc12

InChI Key InChIKey=SPKADRVVYHYAOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676769   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676769((R)-5-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4- | U...)
Affinity DataIC50: 12.6nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent