BDBM676765 2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H-pyrrolo[2,3-::US20240166651, Example 6

SMILES CN(C1CCN(C1)C(C(O)=O)c1ccc(Cl)cc1F)c1ncnc2[nH]ccc12

InChI Key InChIKey=TVQMLRJSXGSETN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676765   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676765(2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H-pyrrol...)
Affinity DataIC50: 5.01E+3nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent