BDBM676629 US20240166643, Example 88

SMILES COc1cnc(nc1N1CC(C1)C(=O)NC(C)(C)c1cnc2ccccn12)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=UMCZNZVMKSKTAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676629   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676629(US20240166643, Example 88)
Affinity DataIC50: 0.0210nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676629(US20240166643, Example 88)
Affinity DataIC50: 0.0110nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent