BDBM676618 US20240166643, Example 75::US20240166643, Example 76

SMILES CN1CCN(CC1)c1ncc(Cl)c(n1)N1CCC(C1)C(=O)NC(C)(C)c1cnc2ccccn12

InChI Key InChIKey=FNUYKZDPUKOIRL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 676618   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676618(US20240166643, Example 75 | US20240166643, Example...)
Affinity DataIC50: 0.25nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676618(US20240166643, Example 75 | US20240166643, Example...)
Affinity DataIC50: 0.0350nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676618(US20240166643, Example 75 | US20240166643, Example...)
Affinity DataIC50: 0.0560nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676618(US20240166643, Example 75 | US20240166643, Example...)
Affinity DataIC50: 0.00500nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent