BDBM676549 PF-03531549::US20240166643, Comparative Example 2

SMILES CN(C)CCNc1ncc(Cl)c(n1)N1CC(C1)C(=O)NCc1ccc(F)cc1F

InChI Key InChIKey=ALMPYYUVDQUXFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 676549   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676549(PF-03531549 | US20240166643, Comparative Example 2)
Affinity DataIC50: 7.70nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676549(PF-03531549 | US20240166643, Comparative Example 2)
Affinity DataIC50: 2nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676549(PF-03531549 | US20240166643, Comparative Example 2)
Affinity DataIC50: 1.15E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 2(Human)
State University of Paraiba

Curated by ChEMBL
LigandPNGBDBM676549(PF-03531549 | US20240166643, Comparative Example 2)
Affinity DataIC50: 1.61E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed