BDBM676534 US20240166642, Example 19b

SMILES FC(F)[C@@H]1CCN[C@@H](C1)c1ccccc1Cn1c2cc[nH]c2c(=O)[nH]c1=S

InChI Key InChIKey=GUABFGKQFZNTFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676534   

TargetMyeloperoxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676534(US20240166642, Example 19b)
Affinity DataIC50: 1.30nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetThyroid peroxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676534(US20240166642, Example 19b)
Affinity DataIC50: 570nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent