BDBM676510 US20240166642, Example 4a

SMILES Clc1ccc(Cn2c3cc[nH]c3c(=O)[nH]c2=S)c(c1)[C@H]1COCCN1

InChI Key InChIKey=NNRYKNVTEOHNOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676510   

TargetMyeloperoxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676510(US20240166642, Example 4a)
Affinity DataIC50: 18.7nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetThyroid peroxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676510(US20240166642, Example 4a)
Affinity DataIC50: 370nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent