BDBM676202 Racemic 7-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1- y1)-6-fluoro-1-isopropyl-3-methyl-3-(o-toly1)-2,3-dihydroquinolin-4(1H)-one::US20240166622, Example 19

SMILES CCn1c(CO)nn(-c2cc3N(CC(C)(C(=O)c3cc2F)c2ccccc2C)C(C)C)c1=O

InChI Key InChIKey=APLIEOYHQQJOTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676202   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Biotech, Inc.

US Patent
LigandPNGBDBM676202(US20240166622, Example 19 | Racemic 7-(4-Ethyl-3-(...)
Affinity DataIC50: 7.06nMAssay Description:To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from the...More data for this Ligand-Target Pair
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Date in BDB:
8/26/2024
Entry Details
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