BDBM676125 US20240166598, Example 42

SMILES C[C@@H](NC(=O)c1cc(ccc1C)N(C)C1CNC1)c1cccc2[nH]ccc12

InChI Key InChIKey=FHQQGSAOPVPVIY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676125   

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandPNGBDBM676125(US20240166598, Example 42)
Affinity DataIC50: 7.00E+3nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandPNGBDBM676125(US20240166598, Example 42)
Affinity DataKd:  3.22E+4nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent