BDBM675951 3-((S)-3-((R)-8-(4'-(aminomethyl)-4-ethoxybiphenyl-3-ylsulfonyl)-1-oxa-8-azaspiro[4.5]decan-3-ylamino)-2-hydroxypropoxy)-N-methylbenzenesulfonamide::US11987588, Compound 420

SMILES CCOc1ccc(cc1S(=O)(=O)N1CCC2(C[C@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)NC)CC1)-c1ccc(CN)cc1

InChI Key InChIKey=DHXGJILMRONDSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675951   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM675951(US11987588, Compound 420 | 3-((S)-3-((R)-8-(4'-(am...)
Affinity DataIC50: 10.2nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
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Date in BDB:
8/22/2024
Entry Details
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