BDBM675752 3-((2S)-2-hydroxy-3-(8-(1-methyl-1H-indol-5-ylsulfonyl)-1-oxa-8-azaspiro[4.5]decan-3-ylamino)propoxy)-N-methylbenzenesulfonamide::US11987588, Compound 221

SMILES CNS(=O)(=O)c1cccc(OC[C@@H](O)CNC2COC3(C2)CCN(CC3)S(=O)(=O)c2ccc3n(C)ccc3c2)c1

InChI Key InChIKey=XBFHXINGGZIWSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675752   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM675752(3-((2S)-2-hydroxy-3-(8-(1-methyl-1H-indol-5-ylsulf...)
Affinity DataIC50: 9.58nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
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Date in BDB:
8/22/2024
Entry Details
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