BDBM675306 US20240158414, Example 62

SMILES CC(Oc1cc(c(F)cc1C(=O)Nc1c(C)n[nH]c1Cl)-c1ccc(cn1)C1CC1)C(F)(F)F

InChI Key InChIKey=ZERQUSGTCBYXCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675306   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Biotech

US Patent
LigandPNGBDBM675306(US20240158414, Example 62)
Affinity DataIC50: 0.229nMAssay Description:DHODH Enzymatic Assay: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
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