BDBM675218 Synthesis of Compound YL131::US20240158408, Compound YL131

SMILES Fc1cc(cc(c1)C(F)(F)F)C(=O)Nc1cc(c2CCN3c2c1C(NC3=O)c1cc(Cl)ccc1Cl)-c1cccnc1C#N

InChI Key InChIKey=SOQQOCMFPUTLBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 675218   

LigandPNGBDBM675218(Synthesis of Compound YL131 | US20240158408, Compo...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
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LigandPNGBDBM675218(Synthesis of Compound YL131 | US20240158408, Compo...)
Affinity DataIC50: 200nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent