BDBM674948 4-chloro-2-(difluoromethyl)-N-((1S,2R)-2-(6- fluoro-2,3-dimethylphenyl)-1-(2H-tetrazol-5- yl)propyl)benzenesulfonamide::US20240158383, Example 50::US20240158383, Example 51

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)cc1C(F)F)c1nn[nH]n1)c1c(F)ccc(C)c1C

InChI Key InChIKey=QVDVHGZETDHAIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674948   

LigandPNGBDBM674948(US20240158383, Example 51 | 4-chloro-2-(difluorome...)
Affinity DataIC50: 550nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

LigandPNGBDBM674948(US20240158383, Example 51 | 4-chloro-2-(difluorome...)
Affinity DataIC50: 550nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent