BDBM674899 (R)-5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(2H-tetrazol-5-yl)propyl)-4-hydroxy-4-methylchromane-8-sulfonamide::US20240158383, Example 12::US20240158383, Example 3::US20240158383, Example 4::US20240158383, Example 7

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@@]2(C)O)c1nn[nH]n1)c1c(F)ccc(C)c1C

InChI Key InChIKey=CPRSWOSUVLCIRU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 674899   

LigandPNGBDBM674899(US20240158383, Example 4 | (R)-5-chloro-N-((1S,2R)...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

LigandPNGBDBM674899(US20240158383, Example 4 | (R)-5-chloro-N-((1S,2R)...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

LigandPNGBDBM674899(US20240158383, Example 4 | (R)-5-chloro-N-((1S,2R)...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

LigandPNGBDBM674899(US20240158383, Example 4 | (R)-5-chloro-N-((1S,2R)...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent