BDBM674897 4-chloro-N-[(1S,2R)-2-(6-fluoro-2,3- dimethylphenyl)-1-(2H-1,2,3,4-tetrazol-5- yl)propyl]-2-methoxybenzene-1-sulfonamide::US20240158383, Example 1::US20240158383, Example 54

SMILES COc1cc(Cl)ccc1S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1nn[nH]n1

InChI Key InChIKey=WDWMUTAKVCIRKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674897   

LigandPNGBDBM674897(4-chloro-N-[(1S,2R)-2-(6-fluoro-2,3- dimethylpheny...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

LigandPNGBDBM674897(4-chloro-N-[(1S,2R)-2-(6-fluoro-2,3- dimethylpheny...)
Affinity DataIC50: 100nMAssay Description:A rapid-fire mass spectrometry (RFMS) assay was used to assess RNR enzyme activity using a 384 well plate and a robotic platform. The plate layout in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent