BDBM674542 ((3R,5R)-3-amino-5- fluoropiperidin-1-yl)(2- (4- (cyclopropylmethyl)- 4H-thieno[3,2-b]pyrrol- 5-yl)-7-methoxy-1- methyl-1H- benzo[d]imidazol-5- yl)methanone::US11981680, Example 30

SMILES COc1cc(cc2nc(-c3cc4sccc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)C[C@@H](F)C1

InChI Key InChIKey=YPXBNWXLJSPJQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674542   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674542(((3R,5R)-3-amino-5- fluoropiperidin-1-yl)(2- (4- (...)
Affinity DataIC50: 86nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent